Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708)

Autor: K. Zwart, M.N.G.J.A. Braat, F.H. van der Baan, A.M. May, J.M.L. Roodhart, D. Al-Toma, J.M.M.B. Otten, M. Los, T. Oostergo, R.J.A. Fijneman, J.M. van Dodewaard-de Jong, C.J.A Punt, G. Meijer, J.J.W. Lagendijk, M. Koopman, M. Intven, G.M. Bol
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical and Translational Radiation Oncology, Vol 49, Iss , Pp 100874- (2024)
Druh dokumentu: article
ISSN: 2405-6308
DOI: 10.1016/j.ctro.2024.100874
Popis: Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasibility and safety. Results indicate that radiotherapy combined with systemic therapy is feasible and safe in this population.
Databáze: Directory of Open Access Journals