| Autor: |
Bradley A. Ruple, Joshua S. Godwin, Paulo H. C. Mesquita, Shelby C. Osburn, Casey L. Sexton, Morgan A. Smith, Jeremy C. Ogletree, Michael D. Goodlett, Joseph L. Edison, Arny A. Ferrando, Andrew D. Fruge, Andreas N. Kavazis, Kaelin C. Young, Michael D. Roberts |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Frontiers in Physiology, Vol 12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1664-042X |
| DOI: |
10.3389/fphys.2021.728683 |
| Popis: |
Resistance training increases muscle fiber hypertrophy, but the morphological adaptations that occur within muscle fibers remain largely unresolved. Fifteen males with minimal training experience (24±4years, 23.9±3.1kg/m2 body mass index) performed 10weeks of conventional, full-body resistance training (2× weekly). Body composition, the radiological density of the vastus lateralis muscle using peripheral quantitative computed tomography (pQCT), and vastus lateralis muscle biopsies were obtained 1week prior to and 72h following the last training bout. Quantification of myofibril and mitochondrial areas in type I (positive for MyHC I) and II (positive for MyHC IIa/IIx) fibers was performed using immunohistochemistry (IHC) techniques. Relative myosin heavy chain and actin protein abundances per wet muscle weight as well as citrate synthase (CS) activity assays were also obtained on tissue lysates. Training increased whole-body lean mass, mid-thigh muscle cross-sectional area, mean and type II fiber cross-sectional areas (fCSA), and maximal strength values for leg press, bench press, and deadlift (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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