Prevalence of multidrug resistance among retreatment pulmonary tuberculosis cases in a tertiary care hospital, Hyderabad, India
| Autor: | Subhakar Kandi, Surapaneni Venkateswara Prasad, P Navaneeth Sagar Reddy, Vennaposa Chenna Kishore Reddy, Rajya Laxmi, Dhanamurthy Kopuu, Kiran Kumar Kondapaka, M S Sreenivas Rao, P H Vishnu |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Lung India, Vol 30, Iss 4, Pp 277-279 (2013) |
| Druh dokumentu: | article |
| ISSN: | 0970-2113 0974-598X |
| DOI: | 10.4103/0970-2113.120599 |
| Popis: | Background: India is one of the high tuberculosis (TB) burden countries in the world. India ranks second in harboring multi drug resistant (MDR)-TB cases. About 50,000 of MDR cases are recorded in retreatment pulmonary TB cases. This study was conducted in a tertiary care facility (Government General and Chest Hospital) in Hyderabad, India. Objectives: Toassess: Proportion of the TB patients having MDR-TB at the initiation of retreatment regimen; the prevalence of isoniazid (INH) resistance in this geographical area. Materials and Methods: An analytical, observational, prospective cohort study of patients attending the out-patient department from December 2010 to March 2011. Results: Sputum samples from 100 patients were subjected to acid fast bacilli (AFB) culture and drug sensitivity testing. Of these, 28 (28%) were MDR-TB, 42 (42%) were non-MDR-TB and 39% being INH resistance. Conclusions: In conclusion, one third of the retreatment pulmonary TB cases attending a tertiary care institute for TB will be MDR-TB at the initiation of treatment and there is a need to include ethambutol in the continuation phase of new TB case treatment in view of high INH resistance. |
| Databáze: | Directory of Open Access Journals |
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