Rituximab in Patients With Phospholipase A2 Receptor–Associated Membranous Nephropathy and Severe CKD

Autor: Nicolas Hanset, Emmanuel Esteve, Emmanuelle Plaisier, Catherine Johanet, Pierre-Antoine Michel, Jean-Jacques Boffa, Patrick Fievet, Laurent Mesnard, Johann Morelle, Pierre Ronco, Karine Dahan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Kidney International Reports, Vol 5, Iss 3, Pp 331-338 (2020)
Druh dokumentu: article
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2019.12.006
Popis: Introduction: Patients with phospholipase A2 receptor (PLA2R)–associated membranous nephropathy and stage 4 or 5 chronic kidney disease are at high risk of end-stage kidney disease. In recent years, rituximab (RTX) emerged as a safe and efficient treatment for patients with PLA2R-associated membranous nephropathy. Whether its use is also appropriate in patients with an estimated glomerular filtration rate
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