Double Perforation after Colorectal Cancer Surgery During Bevacizumab Treatment

Autor:	Lucian Sorin ANDREI, Radu Sorin POPISTEANU, Adriana ANDREI, Alexandru MICU, Ioana DINU
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	bevacizumab metastasized colorectal cancer ischemic perforation Medicine Medicine (General) R5-920
Zdroj:	Modern Medicine, Vol 27, Iss 4, Pp 309-312 (2020)
Druh dokumentu:	article
ISSN:	1223-0472 2360-2473
DOI:	10.31689/rmm.2020.27.4.309
Popis:	Bevacizumab is a monoclonal antibody which has shown promising results in the treatment of varied malignant pathology, including metastasized colorectal cancer. It acts by inhibiting VEGF (vascular endothelial growth factor), and one of its most cited complications is intestinal perforation, by mechanisms which are not yet fully understood. We present the case of a 68 year old patient, operated for metastasized colorectal cancer, which underwent chemotherapy with Bevacizumab, and shortly after initiating therapy developed fistula of low colorectal anastomosis, followed by ischemic perforation of the small intestine.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ce1031625a034217a1ad690ae4c09532 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF