Structure of the Arabidopsis guard cell anion channel SLAC1 suggests activation mechanism by phosphorylation

Autor: Yawen Li, Yinan Ding, Lili Qu, Xinru Li, Qinxuan Lai, Pingxia Zhao, Yongxiang Gao, Chengbin Xiang, Chunlei Cang, Xin Liu, Linfeng Sun
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-30253-3
Popis: The anion channel SLAC1 controls stomatal closure upon phosphoactivation. Here via structural analysis and electrophysiology, the authors propose an inhibition-release model where phosphorylation causes dissociation of a cytosolic plug from the SLAC1 transmembrane domains to induce conformational change in the pore-forming helices.
Databáze: Directory of Open Access Journals
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