Mantle Cell Lymphoma Presenting as Multiple Lymphomatous Polyposis of the Colon

Autor: Syed Shafiq, Ganesh Narayan Ramesh, Varun Khandagale
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Digestive Endoscopy, Vol 11, Iss 02, Pp 149-152 (2020)
Druh dokumentu: article
ISSN: 0976-5042
0976-5050
DOI: 10.1055/s-0040-1713288
Popis: Mantle cell lymphoma (MCL) is a subset of B-cell non-Hodgkin’s lymphoma with a tendency to involve the gastrointestinal (GI) tract and presents as multiple lymphomatous polyposis of one or multiple segments of the GI tract. Here, we report an unusual case of a 58-year-old female presenting with chief complaints of constipation, bleed per rectum, and unintentional weight loss of 15 kg over 6 months. Colonoscopy revealed the entire colon to be studded with polypoidal lesions of varying sizes which were biopsied. Histopathological examination and immunohistochemistry confirmed the polypoidal lesions to represent MCL. Computed tomography scan showed numerous variable-sized polypoidal lesions scattered throughout the entire colon along with paraaortic and mesenteric lymphadenopathy. Thus far, she has undergone three cycles of chemotherapy with R-CHOP resulting in significant tumor reduction and symptomatic improvement in her well-being.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje