Invasive aspergillosis related to ibrutinib therapy for chronic lymphocytic leukemia

Autor: Benjamin Arthurs, MD, Kathy Wunderle, MD, Maylee Hsu, MD, Suil Kim, MD, PhD
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 21, Iss C, Pp 27-29 (2017)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2017.03.011
Popis: We report a case of invasive pulmonary aspergillosis in a patient taking ibrutinib, a Bruton's tyrosine kinase inhibitor used to treat refractory chronic lymphocytic leukemia. We hypothesize that ibrutinib promoted this infection by suppressing innate immune responses against Aspergillus. Clinicians should be aware of potential Aspergillus infections in patients treated with this drug.
Databáze: Directory of Open Access Journals