Inferior intravitreal injection site associated with a higher incidence of post-injection endophthalmitis

Autor: Gowtham Jonna, Daniel B. Roth, Howard F. Fine, H. Matthew Wheatley, Jonathan L. Prenner, Arvin Kheterpal, Suzanne Cohen, William J. Feuer
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 15, Iss 5, Pp 750-754 (2015)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2015.5.02
Popis: AIM:To determine whether inferior injections had a higher incidence of post-injection endophthalmitis than superior injections. The incidence of endophthalmitis is higher for inferior than superior trabeculectomy filtering blebs, possibly due to bacteria pooling in the inferior tear lake. METHODS: A practice-wide database of endophthalmitis cases identified 5 occurring during the two-year study period. A retrospective review of 8 672 injections in 1 121 eyes of 909 patients treated during the same two-year study period was performed in order to assess the injection site location.RESULTS: Five eyes developed presumed infectious endophthalmitis. Eighty percent of endophthalmitis cases were injected inferiorly, even though 84.6% of the total cohort was injected superiorly. The odds ratio of infection associated with inferior injection location is 22.1(P=0.006).CONCLUSION:Endophthalmitis after intravitreal injection is rare, occurring in only 0.025% of injections overall. Avoiding intravitreal injections in the inferior quadrants may further reduce the rate of endophthalmitis.
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