Exploring the potential of ex-vivo 7-T magnetic resonance imaging on patients with clinically significant prostate cancer: visibility and size perspective

Autor: Hyungwoo Ahn, Jung Kwon Kim, Sung Il Hwang, Sung Kyu Hong, Seok-Soo Byun, Sang Hun Song, Gheeyoung Choe, Hye Mi Jee, Sung Woo Park
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Prostate International, Vol 12, Iss 2, Pp 79-85 (2024)
Druh dokumentu: article
ISSN: 2287-8882
DOI: 10.1016/j.prnil.2024.02.001
Popis: Background: Despite progress in multiparametric magnetic resonance imaging (MRI), issues of prostate cancer invisibility and underestimated tumor burden persist. This study investigates the potential of an ultra-high field MRI at 7-T in an ex-vivo setting to address these limitations. Methods: This prospective study included 54 tumors from 20 treatment-naïve clinically significant prostate cancer patients, confirmed by biopsy, despite negative findings on preoperative 3-T MRI. Ex-vivo 7-T MRI of resected prostates was performed, with assessment on tumor visibility and size. Factors influencing visibility were analyzed using logistic regression analyses. Results: Tumor visibility was confirmed in 80% of patients, and 48% of all tumors on ex-vivo imaging. Gleason pattern 4 percentage (odds ratio 1.09) and tumor size on pathology (odds ratio 1.36) were significantly associated with visibility (P
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