No gene by stressful life events interaction on individual differences in adults’ self-control

Autor: Yayouk Eva Willems, Laurel Raffington, Lannie Ligthart, Rene Pool, Jouke Jan Hottenga, Catrin Finkenauer, Meike Bartels
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Psychiatry, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2024.1388264
Popis: BackgroundDifficulty with self-control, or the ability to alter impulses and behavior in a goal-directed way, predicts interpersonal conflict, lower socioeconomic attainments, and more adverse health outcomes. Etiological understanding, and intervention for low self-control is, therefore, a public health goal. A prominent developmental theory proposes that individuals with high genetic propensity for low self-control that are also exposed to stressful environments may be most at-risk of low levels of self-control. Here we examine if polygenic measures associated with behaviors marked by low self-control interact with stressful life events in predicting self-control.MethodsLeveraging molecular data from a large population-based Dutch sample (N = 7,090, Mage = 41.2) to test for effects of genetics (i.e., polygenic scores for ADHD and aggression), stressful life events (e.g., traffic accident, violent assault, financial problems), and a gene-by-stress interaction on self-control (measured with the ASEBA Self-Control Scale).ResultsBoth genetics (β =.03 -.04, p
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