Factors influencing cancer genetic somatic mutation test ordering by cancer physician

Autor: Anastassia Demeshko, David J. Pennisi, Sushil Narayan, Stacy W. Gray, Matthew A. Brown, Aideen M. McInerney-Leo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1479-5876
DOI: 10.1186/s12967-020-02610-7
Popis: Abstract Background Clinical whole exome sequencing was introduced in an Australian centre in 2017, as an alternative to Sanger sequencing. We aimed to identify predictors of cancer physicians’ somatic mutation test ordering behaviour. Methods A validated instrument assessed somatic mutation test ordering, genomic confidence, perceived utility of tumour molecular profiling, and percent of patients eligible for targeted therapy. A cash incentive was included in 189/244 questionnaires which were mailed to all Queensland cancer specialists in November 2018. Results 110 participated (response rate 45%); 54.7% oncologists, and the remainder were surgeons, haematologists and pulmonologists. Oncologists were more likely to respond (p = 0.008), and cash incentive improved the response rate (p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje