THE STATE OF NITROXIDE PRODUCTION FUNCTION OF ENDOTHELIUM AND LEFT VENTRICLE HYPERTROPHY IN ARTERIAL HYPERTENSION
| Autor: | V. I. Podzolkov, A. E. Bragina, G. I. v, N. A. Murashko |
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| Jazyk: | ruština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 16, Iss 4, Pp 11-17 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| DOI: | 10.15829/1728-8800-2017-4-11-17 |
| Popis: | Aim. To assess levels of stable nitric oxide metabolites (NO) in plasma of arterial hypertension (AH) patients not taking systematic antihypertension therapy, in accordance with the presence and absence of the left ventricle hypertrophy (LVH).Material and methods. Totally, 124 AH patients included: 45 males, 79 females, mean age — 51,4±6,5 y.o., mean duration of AH — 7,9±7,3 y. Controls included 25 healthy persons: 10 males, 15 females; mean age — 48,2±7,8 y.o. Transthoracal echocardiography was done by standard method. Myocardium remodelling types were evaluated by the Ganau A (1992) criteria. Concentration of NO in plasma was measured by spectrophotometry. Statistics was done with Statistica 8.0 software.Results. In AH patients the level of NO was significantly higher than in controls — 43,2±21,7 mcM/L vs 28,3±9,6 mcM/L (p |
| Databáze: | Directory of Open Access Journals |
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