MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE
| Autor: | M. A. Shakhnazarov, A. M. Shakhnazarov, M. T. Rasulov, B. G. Magomedgadzhiev, A. O. Medzhidov |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Юг России: экология, развитие, Vol 6, Iss 3, Pp 112-117 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1992-1098 2413-0958 |
| Popis: | On the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dose of the administrated pesticide up to 50-100 MPC the aggressive course of ulcer with an increase of the frequency of its penetration into liver (up to 100% in the dose of 100 MPC) and op-pression of the activity of all the dehydrogenases, MAO, strengthening of glycogenolysis, the drop of RNA synthesis in hepa-tocytes are noticed. Simultaneously, the raised activity of acid phosphatase, alkaline phosphatase is saved that testifies to activization of hydrolytic and fibroblastic processes of the defensive nature. |
| Databáze: | Directory of Open Access Journals |
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