Polymorphisms of MicroRNA-146a Gene in Behcet’s Disease in Iraqi Patients
| Autor: | Israa Harjan Mohsen, Mona N. Al-Terehi, Abbas Hussein Mugheer, Ahmed Al-Hachamy, Ali H. Al-Saadi |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Pure and Applied Microbiology, Vol 12, Iss 3, Pp 1579-1582 (2018) |
| Druh dokumentu: | article |
| ISSN: | 0973-7510 2581-690X |
| DOI: | 10.22207/JPAM.12.3.63 |
| Popis: | The present study was carried out to detect the association of miR-146a haplotypes polymorphisms with Behcet’s Disease in Iraqi patients, PCR-SSCP technique used in present study, blood was used to DNA extraction, the results show that there was strong association between miR-146a and Behçet’s Disease there were two patterns (A and B), polymorphisms show significant differences (p>0.05) between patients and control where haplotype A was appeared in control with (4% ) while in patients (43%) and haplotype B was appeared in control with (96% ) while in patients (57%). The present study concluded that there was association between miR-146a polymorphisms with Behçet’s Disease, our finding need more investigation to use this polymorphism as early indication of Behçet’s Disease incidence. |
| Databáze: | Directory of Open Access Journals |
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