A Case of Metastatic Collecting Duct Carcinoma Whose Massive Skull Bone Metastasis was Prominently Reossified by Gemcitabine Plus Cisplatin Chemotherapy Combined with Zoledronic Acid

Autor: Makoto Kawaguchi, Keiichi Ito, Hideyuki Shimazaki, Tomohiko Asano
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Urology Case Reports, Vol 15, Iss C, Pp 14-16 (2017)
Druh dokumentu: article
ISSN: 2214-4420
DOI: 10.1016/j.eucr.2017.07.002
Popis: The present case underwent right laparoscopic radical nephrectomy for collecting duct carcinoma (CDC). Recurrence occurred in the lung and the bone (skull and lumber vertebra) in 2011. Gemcitabine plus cisplatin (GC) chemotherapy and monthly zoledronic acid (ZA) was then started. The massive skull bone metastases were prominently reossified after several courses of the therapy. The patient received 16 courses of GC chemotherapy and monthly ZA, and pulmonary metastases and reossified skull bone metastases were stable for 23 months. Although we cannot verify the adoptive effect of ZA on the reossification, this combination may be effective for CDC bone metastases.
Databáze: Directory of Open Access Journals