Evaluation of the blood neutrophil‐to‐lymphocyte ratio as a biomarker for meningoencephalitis of unknown etiology in dogs

Autor: Jooyoung Park, Dohee Lee, Taesik Yun, Yoonhoi Koo, Yeon Chae, Hakhyun Kim, Mhan‐Pyo Yang, Byeong‐Teck Kang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Veterinary Internal Medicine, Vol 36, Iss 5, Pp 1719-1725 (2022)
Druh dokumentu: article
ISSN: 1939-1676
0891-6640
DOI: 10.1111/jvim.16512
Popis: Abstract Background The neutrophil‐to‐lymphocyte ratio (NLR) has been identified as a biomarker in several inflammatory and autoimmune diseases. Multiple sclerosis (MS) has been found to be associated with changes in the NLR in humans. Objectives To examine the diagnostic value of the NLR in meningoencephalitis of unknown etiology (MUE) in dogs. Animals Thirty‐eight MUE dogs, 20 hydrocephalic dogs, 10 brain tumor (BT) dogs, 32 idiopathic epilepsy (IE) dogs, and 41 healthy dogs. Methods Retrospective study. Medical records were reviewed to identify dogs with a diagnosis of neurologic disease. The NLR was determined in all dogs. Results The median NLR was significantly higher in MUE dogs (6.08) than in healthy (1.78, P
Databáze: Directory of Open Access Journals
Externí odkaz: