Psychological factors may affect the quality of life in irritable bowel syndrome patients more than the gut itself? A multicenter cross‐sectional study

Autor: Xiaotian Xie, Jing He, Shu Xu, Zhiyue Xu, Yanqin Long, Zhijun Duan, Jie Yang, Zhifeng Zhang, Jun Wu, Lianying Cai, Liexin Liang, Ning Dai, Jun Zhang, Tao Bai, Xiaohua Hou
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JGH Open, Vol 8, Iss 3, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2397-9070
DOI: 10.1002/jgh3.13045
Popis: Abstract Background and Aim Both intestinal symptoms and comorbidities exist in irritable bowel syndrome (IBS) patients and influence their quality of life (QOL). More research is needed to determine how these variables impact the QOL of IBS patients. This study aimed to determine which specific factors had a higher influence on QOL and to further compare the effects of intestinal symptoms and comorbidities on QOL. Methods IBS patients were recruited from six tertiary hospitals in different regions of China. QOL, gastrointestinal symptoms, and comorbidities were assessed by different scales. Correlation analysis, multiple linear regression, and mediation model were used for statistics. Results Four hundred fifty‐three IBS patients (39.7% women, mean age 45 years) were included and no significant differences in QOL were found across demographic characteristics. Abnormal defecation (r = −0.398), fatigue (r = −0.266), and weakness (r = −0.286) were found to show higher correlation with QOL. More than 40% of IBS patients were found to suffer from varying degrees of anxiety or depression, and anxiety (r = −0.564) and depression (r = −0.411) were significantly negatively correlated with QOL (P
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