Long-term efficacy of Magnolia Bark Extract and Xylitol administered through chewing gums on caries in adults: A 2-year randomized controlled intervention trial

Autor: Maria Grazia Cagetti, Fabio Cocco, Giovanna Carta, Cinzia Maspero, Guglielmo Campus
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Functional Foods, Vol 68, Iss , Pp 103891- (2020)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2020.103891
Popis: Caries preventive effect of a sugar-free chewing-gum containing Magnolia Bark Extracts and Xylitol in high-risk adults was investigated (NCT02310308). Two-hundred seventy-one high-caries-risk subjects were assigned to three groups: Polyols (Pols), Xylitol (Xyl) and Xylitol plus Magnolia (Xyl + Mag). Caries lesions, gingival bleeding, mutans streptococci (MS), and plaque pH were re-evaluated after 2 years in 64 Pols, 66 Xyl and 64 Xyl + Mag subjects. Net caries increment was evaluated using the Mann–Whitney U test. Caries increment was significantly different among groups at the 2-year evaluation (t3) (p
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