Association of Systemic Vascular Resistance Analog and Cardiovascular Outcomes: The Heart and Soul Study

Autor: Dai‐Yin Lu, Qizhi Fang, Dwight Bibby, Bhaskar Arora, Nelson B. Schiller
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.122.026016
Popis: Background Systemic vascular resistance (SVR) is an integral component of the hemodynamic profile. Previous studies have demonstrated a close correlation between an estimated SVR analog (eSVR) based on echocardiographic methods and SVR by direct hemodynamic measurement. However, the prognostic impact of eSVR remains unestablished. Methods and Results Study participants with established coronary artery disease from the Heart and Soul Study formed this study cohort. We defined Doppler‐derived eSVR as the ratio of systolic blood pressure to left ventricular outflow tract velocity time integral. Study participants were separated based on baseline eSVR tertile:
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