Bariatric surgery for non-alcoholic fatty liver disease in individuals with obesity (Base-NAFLD): protocol of a prospective multicenter observational follow-up study

Autor: Luyang Wei, Mengyi Li, Na Zeng, Yang Liu, Rixing Bai, Nengwei Zhang, Jinghai Song, Pin Zhang, Qiyuan Yao, Zhenghan Yang, Xinyan Zhao, Yun Zhang, Peng Zhang, Zhongtao Zhang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Surgery, Vol 21, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 1471-2482
68891547
DOI: 10.1186/s12893-021-01296-y
Popis: Abstract Background Bariatric surgery may be indicated in patients with nonalcoholic fatty liver disease (NAFLD) to achieve and maintain the degree of weight loss required to ensure therapeutic effects. However, bariatric surgery is still underrecognized in the treatment of NAFLD, including its inflammatory subtype, nonalcoholic steatohepatitis (NASH). Moreover, there is a lack of follow-up outcome data on different types of bariatric surgery in patients with NAFLD. This study aims to adequately assess the effect of bariatric surgery on NAFLD remission in obese patients. Methods This prospective multicentre observational follow-up study will include 142 obese patients with NAFLD scheduled to undergo one of the following surgical procedures: sleeve gastrostomy, Roux-en-Y gastric bypass, and one anastomosis gastric bypass. The primary outcome is the complete remission rate of NAFLD one year postoperatively, which is defined by liver fat fraction
Databáze: Directory of Open Access Journals
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