Longitudinal SARS-CoV-2 Nucleocapsid Antibody Kinetics, Seroreversion, and Implications for Seroepidemiologic Studies

Autor:	Michael Loesche, Elizabeth W. Karlson, Opeyemi Talabi, Guohai Zhou, Natalie Boutin, Rachel Atchley, Gideon Loevinsohn, Jun Bai Park Chang, Mohammad A. Hasdianda, Adetoun Okenla, Elizabeth Sampson, Haley Schram, Karen Magsipoc, Kirsten Goodman, Lauren Donahue, Maureen MacGowan, Lewis A. Novack, Petr Jarolim, Lindsey R. Baden, Eric J. Nilles
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 coronaviruses viruses COVID-19 coronavirus disease Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 28, Iss 9, Pp 1859-1862 (2022)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2809.220729
Popis:	Given widespread use of spike antibody in generating coronavirus disease vaccines, SARS-CoV-2 nucleocapsid antibodies are increasingly used to indicate previous infection in serologic surveys. However, longitudinal kinetics and seroreversion are poorly defined. We found substantial seroreversion of nucleocapsid total immunoglobulin, underscoring the need to account for seroreversion in seroepidemiologic studies.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a0f7746101884898a03c9acecc93994f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF