De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing

Autor: Eskild Petersen, Faryal Khamis, Giovanni Battista Migliori, Julie Glerup Bay, Ben Marais, Christian Wejse, Alimuddin Zumla
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 56, Iss C, Pp 34-38 (2017)
Druh dokumentu: article
ISSN: 1201-9712
1878-3511
DOI: 10.1016/j.ijid.2017.01.029
Popis: The study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-pressure isolation and de-isolation patients from either single rooms or isolation at home is needed. Studies show that the time of effective treatment is the key parameter to follow to determine if patients are contagious to others or not. This means that standard treatment of multi-drug resistant, MDR, TB will not result in the patient being non-infectious. Thus it is important right from the time of diagnosis to know if the patient is infected with MDR TB or not. Thus the early use of molecular techniques to reveal drug susceptibility is important. Clear guidelines stating if patient with microscopy negative sputum no matter infected with fully susceptible or MDR TB, no matter HIV positive or not is needed.
Databáze: Directory of Open Access Journals