Examining the effects of HIV self-testing compared to standard HIV testing services in the general population: A systematic review and meta-analysis

Autor: Muhammad S. Jamil, Ingrid Eshun-Wilson, T. Charles Witzel, Nandi Siegfried, Carmen Figueroa, Lastone Chitembo, Busisiwe Msimanga-Radebe, Muhammad S. Pasha, Karin Hatzold, Elizabeth Corbett, Magdalena Barr-DiChiara, Alison J. Rodger, Peter Weatherburn, Elvin Geng, Rachel Baggaley, Cheryl Johnson
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: EClinicalMedicine, Vol 38, Iss , Pp 100991- (2021)
Druh dokumentu: article
ISSN: 2589-5370
DOI: 10.1016/j.eclinm.2021.100991
Popis: Background: We updated a 2017 systematic review and compared the effects of HIV self-testing (HIVST) to standard HIV testing services to understand effective service delivery models among the general population. Methods: We included randomized controlled trials (RCTs) comparing testing outcomes with HIVST to standard testing in the general population and published between January 1, 2006 and June 4, 2019. Random effects meta-analysis was conducted and pooled risk ratios (RRs) were reported. The certainty of evidence was determined using the GRADE methodology. Findings: We identified 14 eligible RCTs, 13 of which were conducted in sub-Saharan Africa. Support provided to self-testers ranged from no/basic support to one-on-one in-person support. HIVST increased testing uptake overall (RR:2.09; 95% confidence interval: 1.69–2.58; p
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