Efficacy of neoadjuvant chemotherapy combined with surgery in patients with nonsmall cell lung cancer: A meta‐analysis

Autor: Hai‐jun Dong, Cheng‐yan Yang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Clinical Respiratory Journal, Vol 18, Iss 5, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 1752-699X
1752-6981
DOI: 10.1111/crj.13756
Popis: Abstract Introduction This meta‐analysis sought to investigate the effect of neoadjuvant chemotherapy (NACT) combined with surgery in patients with nonsmall cell lung cancer (NSCLC). Methods With time span from January 2010 to December 2022, PubMed, Web of Science and Embase, China National Knowledge Infrastructure, and WanFang databases were searched for randomized controlled trials on comparison between NACT combined with surgery and surgery alone in patients with NSCLC. Then a meta‐analysis was performed in accordance with Preferred Reporting Items for Systematic reviews and Meta‐Analyses (PRISMA) guidelines. Results A total of 1511 studies were retrieved and 12 were finally included. Meta‐analysis results showed that compared with surgery alone, a combination of NACT and surgery was associated with higher treatment response rate (odds ratio, OR = 2.459, 95% confidence interval, CI [1.785, 3.388], P
Databáze: Directory of Open Access Journals
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