Popis: |
Objective:The aim of this study was to assess the effect on various systems of increased Obstructive Sleep Apnea syndrome (OSAS) severity, defined with the Apnea-hypopnea index (AHI).Materials and Methods:The study was conducted on 245 patients who met the inclusion criteria. A total of 8 non-obese obese and obese non-obese groups were formed. There were the non-obese control group [AHI30 kg/m2 (n=28)], non-obese mild OSAS group [AHI 5-15, BMI≤29.9 kg/m2 (n=33)], obese mild OSAS group [AHI 5-15, BMI>30 kg/m2 (n=26)], non-obese moderate OSAS group [AHI 15-30, BMI≤29.9 kg/m2 (n=41)], obese moderate OSAS group [AHI 15-30, BMI>30 kg/m2 (n=24)], non-obese severe OSAS group [AHI> 30, BMI≤29.9 kg/m2 (n=38)], and obese severe OSAS group [AHI>30, BMI>30 kg/m2 (n=23)].Results:A statistically significantly greater difference was determined between the groups in respect of the monocyte HDL cholesterol ratio (MHR), monocyte LDL cholesterol ratio (MLR) and uric acid excretion (UAE) values together with an increase in the severity of OSAS (p |