An Evaluation of the Relationship Between Disease Severity and the Hematological, Biochemical and Hormone Values in Adult Patients with Obstructive Sleep Apnea Syndrome: A Cross-sectional Study

Autor: Mustafa Avcu, Mehmet Metin, Harun Soyalıç, Bilal İlanbey, Elvan Evrim Tuna
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Türk Uyku Tıbbı Dergisi, Vol 7, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 2148-1504
DOI: 10.4274/jtsm.galenos.2020.19484
Popis: Objective:The aim of this study was to assess the effect on various systems of increased Obstructive Sleep Apnea syndrome (OSAS) severity, defined with the Apnea-hypopnea index (AHI).Materials and Methods:The study was conducted on 245 patients who met the inclusion criteria. A total of 8 non-obese obese and obese non-obese groups were formed. There were the non-obese control group [AHI30 kg/m2 (n=28)], non-obese mild OSAS group [AHI 5-15, BMI≤29.9 kg/m2 (n=33)], obese mild OSAS group [AHI 5-15, BMI>30 kg/m2 (n=26)], non-obese moderate OSAS group [AHI 15-30, BMI≤29.9 kg/m2 (n=41)], obese moderate OSAS group [AHI 15-30, BMI>30 kg/m2 (n=24)], non-obese severe OSAS group [AHI> 30, BMI≤29.9 kg/m2 (n=38)], and obese severe OSAS group [AHI>30, BMI>30 kg/m2 (n=23)].Results:A statistically significantly greater difference was determined between the groups in respect of the monocyte HDL cholesterol ratio (MHR), monocyte LDL cholesterol ratio (MLR) and uric acid excretion (UAE) values together with an increase in the severity of OSAS (p
Databáze: Directory of Open Access Journals