Computer-Aided Intra-Operatory Positioning of an MRgHIFU Applicator Dedicated to Abdominal Thermal Therapy Using Particle Swarm Optimization

Autor: Yacine M'Rad, Caecilia Charbonnier, Marcelo Elias de Oliveira, Pauline Coralie Guillemin, Lindsey Alexandra Crowe, Thibaud Koessler, Pierre-Alexandre Poletti, Sana Boudabbous, Alexis Ricoeur, Rares Salomir, Orane Lorton
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 524-533 (2024)
Druh dokumentu: article
ISSN: 2644-1276
DOI: 10.1109/OJEMB.2024.3410118
Popis: Purpose: Transducer positioning for liver ablation by magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) is challenging due to the presence of air-filled organs or bones on the beam path. This paper presents a software tool developed to optimize the positioning of a HIFU transducer dedicated to abdominal thermal therapy, to maximize the treatment's efficiency while minimizing the near-field risk. Methods: A software tool was developed to determine the theoretical optimal position (TOP) of the transducer based on the minimization of a cost function using the particle swarm optimization (PSO). After an initialization phase and a manual segmentation of the abdomen of 5 pigs, the program randomly generates particles with 2 degrees of freedom and iteratively minimizes the cost function of the particles considering 3 parameters weighted according to their criticality. New particles are generated around the best position obtained at the previous step and the process is repeated until the optimal position of the transducer is reached. MR imaging data from in vivo HIFU ablation in pig livers was used for ground truth comparison between the TOP and the experimental position (EP). Results: As compared to the manual EP, the rotation difference with the TOP was on average −3.1 ± 7.1° and the distance difference was on average −7.1 ± 5.4 mm. The computational time to suggest the TOP was 20s. The software tool is modulable and demonstrated consistency and robustness when repeating the calculation and changing the initial position of the transducer.
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