Asymmetrical cortical vessel sign predicts prognosis after acute ischemic stroke

Autor: Yong‐Lin Liu, Wei‐Min Xiao, Jie‐Kai Lu, Ya‐Zhi Wang, Zhi‐Hao Lu, Huo‐Hua Zhong, Jian‐Feng Qu, Xue‐Wen Fang, Man‐Qiu Liang, Yang‐Kun Chen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Brain and Behavior, Vol 10, Iss 7, Pp n/a-n/a (2020)
Druh dokumentu: article
ISSN: 2162-3279
DOI: 10.1002/brb3.1657
Popis: Abstract Introduction To assess whether the asymmetrical cortical vessel sign (ACVS) on susceptibility‐weighted imaging (SWI) could predict 90‐day poor outcomes in anterior circulation acute ischemic stroke (AIS) patients treated with recombinant tissue plasminogen activator (r‐tPA). Methods Clinical data of consecutive patients with anterior circulation AIS treated with r‐tPA were retrospectively analyzed. Clinical variables included age, sex, vascular risk factors, NIHSS score, onset to treatment time, and initial hematologic and neuroimaging findings. Follow‐up was performed 90 days after onset. Poor outcome was defined as a modified Rankin scale (mRS) ≥3 at 90 days. Results A total of 145 patients were included, 35 (24.1%) patients presented with ACVS (≥Grade 1) on SWI. Fifty‐three (36.6%) patients had a poor outcome at 90 days. ACVS (≥Grade 1) occurred in 21 (39.6%) patients with poor outcome compared with 14 (15.2%) patients with favorable outcome (p = .001). Univariate analysis indicated that age, NIHSS score on admission, previous stroke, hemorrhagic transformation, severe intracranial large artery stenosis or occlusion (SILASO), and ACVS were associated with 90‐day poor outcome (p
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