| Autor: |
Seyedeh Azra Shamsdin, Hassan Akrami, Yousef Nikmanesh, Hasti Samani, Mahammad Javad Fattahi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Iranian Journal of Colorectal Research, Vol 11, Iss 2, Pp 79-82 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2783-2430 |
| DOI: |
10.30476/acrr.2023.99923.1184 |
| Popis: |
Background: Helicobacter pylori is a highly prevalent microorganism and risk factor for gastric cancer. In this study, we evaluated the serum levels of PIVKA-II in patients with and without H. pylori.Methods: This study was performed on 90 patients (45 with H. pylori infection and 45 in the control group). After recording demographic information, serum levels of PIVKA-II were measured by the ELISA method.Results: We found no significant difference in PIVKA-II levels between all patients with and without H. pylori infection (P=0.08), but among individuals aged below 40 years old, H. pylori infection was associated with significantly lower serum PIVKA levels in patients vs. controls (P=0.026). Among men, H. pylori infection was associated with a significantly lower serum PIVKA level than controls (P=0.038). Among all H. pylori-infected patients, women had higher PIVKA levels than men (P=0.037).Conclusion: Our results indicate that (i) serum PIVKA-II levels are lower in H. pylori-infected individuals under 40 years old and men than in non-infected controls, and ii) among all H. pylori-infected patients, serum PIVKA-II levels are lower in men than women and in those under 40 years of age compared to those 40 or above. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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