| Autor: |
Friederike Klein, Sven Möbius-Winkler, Laura Bäz, Rüdiger Pfeifer, Michael Fritzenwanger, Stefan Heymel, Marcus Franz, Pawel Aftanski, P. Christian Schulze, Daniel Kretzschmar |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Canadian Respiratory Journal, Vol 2022 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1916-7245 |
| DOI: |
10.1155/2022/7135958 |
| Popis: |
Background. Percutaneous catheter-based ultrasound-assisted thrombolysis (UACDT) is recommended for patients with intermediate-high-risk or high-risk pulmonary embolism (PE) in whom systemic thrombolysis has failed or is contraindicated. Aim. To evaluate the safety and efficiency of UACDT in patients with intermediate-high-risk or high-risk PE. Methods. Between October 2017 and January 2020, we performed UACDT using the EkoSonic™ Endovascular System (EKOS™) in 51 patients (21 males, age 63 ± 18 years) with a sPESI of 1.3 ± 0.7. The EKOS™-catheter was implanted within 24 h after admission. Over 15 hours, 11.5 mg of alteplase was administered per catheter. We evaluated right ventricular stress and cardiac biomarkers before and after UACDT. Results. 24 h post-UACDT, median RV/LV ratio decreased from 1.13 to 0.96 (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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