Magnetic resonance imaging reference values for cardiac morphology, function and tissue composition in adolescentsResearch in context

Autor: Carlos Real, Rocío Párraga, Gonzalo Pizarro, Inés García-Lunar, Ernesto González-Calvo, Jesús Martínez-Gómez, Javier Sánchez-González, Patricia Sampedro, Irene Sanmamed, Mercedes De Miguel, Amaya De Cos-Gandoy, Patricia Bodega, Borja Ibanez, Gloria Santos-Beneit, Valentin Fuster, Rodrigo Fernández-Jiménez
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: EClinicalMedicine, Vol 57, Iss , Pp 101885- (2023)
Druh dokumentu: article
ISSN: 2589-5370
DOI: 10.1016/j.eclinm.2023.101885
Popis: Summary: Background: Cardiovascular magnetic resonance (CMR) is a precise tool for the assessment of cardiac anatomy, function, and tissue composition. However, studies providing CMR reference values in adolescence are scarce. We aim to provide sex-specific CMR reference values for biventricular and atrial dimensions and function and myocardial relaxation times in this population. Methods: Adolescents aged 15–18 years with no known cardiovascular disease underwent a non-contrast 3-T CMR scan between March 2021 and October 2021. The imaging protocol included a cine steady-state free-precession sequence for the analysis of chamber size and function, as well as T2-GraSE and native MOLLI T1-mapping for the characterization of myocardial tissue. Findings: CMR scans were performed in 123 adolescents (mean age 16 ± 0.5 years, 52% girls). Mean left and right ventricular end-diastolic indexed volumes were higher in boys than in girls (91.7 ± 11.6 vs 78.1 ± 8.3 ml/m2, p
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