Autor: |
Takashi Yamamichi, Masayuki Nakao, Kenshiro Omura, Kohei Hashimoto, Junji Ichinose, Yosuke Matsuura, Yoshinao Sato, Katsunori Oikado, Sakae Okumura, Mingyon Mun |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Cancer Treatment and Research Communications, Vol 29, Iss , Pp 100446- (2021) |
Druh dokumentu: |
article |
ISSN: |
2468-2942 |
DOI: |
10.1016/j.ctarc.2021.100446 |
Popis: |
Objective: The coexistence of interstitial lung disease (ILD) is associated with poor prognosis in patients with lung cancer. The tumor doubling time (TDT) of lung cancer reflects cancer aggressiveness and is related to its prognosis. However, the relationship between the TDT of lung cancer and underlying ILD has not been fully evaluated. This study aimed to identify this crucial relationship. Materials and Methods: Patients with lung cancer who underwent surgery between 2007 and 2020 were reviewed retrospectively. The propensity score matching method was used to balance the characteristics of patients with ILD (n = 100) and those without ILD (n = 100). TDT was calculated based on the difference of three-dimensional volumes defined from the two-time CT scans before surgery. We compared the TDT of lung cancer and other characteristics between the two groups. Results: The median TDT of all patients was 149 days. The TDT was significantly shorter in patients with ILD (134 days) than in those without (204 days). The rate of short-term tumor enlargement (TDT |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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