Anti-NMDAR encephalitis in a 19 year old female patient with ovarian teratoma: A case report

Autor: Johnny El Hanna, Codjo Quenum, Abdelilah Arsalane
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European Journal of Obstetrics & Gynecology and Reproductive Biology: X, Vol 11, Iss , Pp 100129- (2021)
Druh dokumentu: article
ISSN: 2590-1613
DOI: 10.1016/j.eurox.2021.100129
Popis: Background: Anti-N-Methyl-d-Aspartate encephalitis is a subcategory of auto-immune encephalitis. It is known for its aggressive presenting symptoms and rapid deterioration, yet it is treatment responsive. It is associated in 50 % to ovarian teratoma. Case: We report the case of a 19 year old female patient presenting for a psychiatric disorder of sudden onset with rapid deterioration. Neurologic imaging was in favor of encephalitis, and CSF studies revealed Anti NMDA receptors. Further abdominal imaging showed a right ovarian teratoma of 4 cm.Laparoscopic ovarian cyst resection was done, and corticotherapy, IVIG and anticonvulsants were given. We report complete resolution of symptoms after 7 months. Conclusion: Anti-NMDA receptor encephalitis with ovarian teratoma is a rare entity with rapid deterioration. Early diagnosis, surgical resection and proper medical treatment are essential for the management of this disease.
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