Ophthalmological impairment in patients with congenital cytomegalovirus infection

Autor: Serena Salomè, Nicola Ciampa, Mariapaola Giordano, Raffaele Raimondi, Eleonora Capone, Claudia Grieco, Clara Coppola, Letizia Capasso, Francesco Raimondi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2296-2360
DOI: 10.3389/fped.2023.1251893
Popis: BackgroundCongenital cytomegalovirus (cCMV) infection is a frequent cause of neurosensory impairment. Ocular abnormalities and visual impairment have been reported in a high percentage of symptomatic infants, whereas they are considered uncommon in asymptomatic ones. The paucity of data has made difficult to reach clear recommendations on the ophthalmological follow-up that should be provided.Methods250 patients with cCMV infection (123 symptomatic) were enrolled and underwent a series of age-appropriate ophthalmologic, audiologic, and neurodevelopmental examinations from 2002 to 2022.ResultsFunduscopic abnormalities were identified at onset in 16/123 (13%) symptomatic infants and in none of the asymptomatic ones (p
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