Autor: |
Yi-Ling Lin, Yu-Pei Chen, Sheng-Yao Wang, Yi-Feng Kao, Chompunut Lumsangkul, Yi-Chen Chen |
Jazyk: |
angličtina |
Rok vydání: |
2025 |
Předmět: |
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Zdroj: |
Poultry Science, Vol 104, Iss 1, Pp 104517- (2025) |
Druh dokumentu: |
article |
ISSN: |
0032-5791 |
DOI: |
10.1016/j.psj.2024.104517 |
Popis: |
Approximately 10,000 metric tons of broiler livers are yielded every year in Taiwan. However, due to unpleasant odor and health concern, these livers are typically discarded as waste in the slaughtering stream in most developed or developed countries. In alignment with global agrocycle policies, a biofunctional chicken-liver hydrolysate (CLH) has been developed. This study was to investigate the effects of CLHs on glucose homeostasis and complications in type II diabetes. Insulin resistance was induced in liver (FL83B) and muscle (C2C12) cells using 30 and 20 ng TNF-α/mL, respectively, resulting in decreased glucose uptake and lower expressions of IRβ, p-Akt/Akt, and p-GSK3/GSK. CLH supplementation significantly upregulated (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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