FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation

Autor: Zhigang Shen, Tao Dong, Hongmei Yong, Chuyin Deng, Changxiu Chen, Xintian Chen, Miaolei Chen, Sufang Chu, Junnian Zheng, Zhongwei Li, Jin Bai
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Druh dokumentu: article
ISSN: 2058-7716
DOI: 10.1038/s41420-024-01919-2
Popis: Abstract Glioblastoma (GBM) is the most common malignant primary brain tumor. Despite comprehensive treatment with traditional surgery, radiotherapy, and chemotherapy, the median survival rate is
Databáze: Directory of Open Access Journals