T1 and T2 mapping for identifying malignant lymph nodes in head and neck squamous cell carcinoma

Autor: Jiangming Qu, Boju Pan, Tong Su, Yu Chen, Tao Zhang, Xingming Chen, Xiaoli Zhu, Zhentan Xu, Tianjiao Wang, Jinxia Zhu, Zhuhua Zhang, Feng Feng, Zhengyu Jin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Imaging, Vol 23, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1470-7330
DOI: 10.1186/s40644-023-00648-6
Popis: Abstract Background This study seeks to assess the utility of T1 and T2 mapping in distinguishing metastatic lymph nodes from reactive lymphadenopathy in patients with head and neck squamous cell carcinoma (HNSCC), using diffusion-weighted imaging (DWI) as a comparison. Methods Between July 2017 and November 2019, 46 HNSCC patients underwent neck MRI inclusive of T1 and T2 mapping and DWI. Quantitative measurements derived from preoperative T1 and T2 mapping and DWI of metastatic and non-metastatic lymph nodes were compared using independent samples t-test or Mann–Whitney U test. Receiver operating characteristic curves and the DeLong test were employed to determine the most effective diagnostic methodology. Results We examined a total of 122 lymph nodes, 45 (36.9%) of which were metastatic proven by pathology. Mean T2 values for metastatic lymph nodes were significantly lower than those for benign lymph nodes (p
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