Autor: |
Nicholas Parsons, Andrei Irimia, Anar Amgalan, Julien Ugon, Kerri Morgan, Sergiy Shelyag, Alex Hocking, Govinda Poudel, Karen Caeyenberghs |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
NeuroImage: Clinical, Vol 38, Iss , Pp 103428- (2023) |
Druh dokumentu: |
article |
ISSN: |
2213-1582 |
DOI: |
10.1016/j.nicl.2023.103428 |
Popis: |
An emerging body of work has revealed alterations in structural (SC) and functional (FC) brain connectivity following mild TBI (mTBI), with mixed findings. However, these studies seldom integrate complimentary neuroimaging modalities within a unified framework. Multilayer network analysis is an emerging technique to uncover how white matter organization enables functional communication. Using our novel graph metric (SC-FC Bandwidth), we quantified the information capacity of synchronous brain regions in 53 mild TBI patients (46 females; age mean = 40.2 years (y), σ = 16.7 (y), range: 18–79 (y). Diffusion MRI and resting state fMRI were administered at the acute and chronic post-injury intervals. Moreover, participants completed a cognitive task to measure processing speed (30 Seconds and Counting Task; 30-SACT). Processing speed was significantly increased at the chronic, relative to the acute post-injury intervals (p = |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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