Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b Infections in Wild Terrestrial Mammals, United States, 2022
| Autor: | Elizabeth J. Elsmo, Arno Wünschmann, Kimberlee B. Beckmen, Liam E. Broughton-Neiswanger, Elizabeth L. Buckles, Jayne Ellis, Scott D. Fitzgerald, Robert Gerlach, Shawna Hawkins, Hon S. Ip, Julia S. Lankton, Erin M. Lemley, Julianna B. Lenoch, Mary L. Killian, Kristina Lantz, Lindsey Long, Roger Maes, Marta Mainenti, Julie Melotti, Megan E. Moriarty, Shotaro Nakagun, Rachel M. Ruden, Valerie Shearn-Bochsler, Danielle Thompson, Mia K. Torchetti, Arnaud J. Van Wettere, Annabel G. Wise, Ailam L. Lim |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Emerging Infectious Diseases, Vol 29, Iss 12, Pp 2451-2460 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1080-6040 1080-6059 75008130 |
| DOI: | 10.3201/eid2912.230464 |
| Popis: | We describe the pathology of natural infection with highly pathogenic avian influenza A(H5N1) virus of Eurasian lineage Goose/Guangdong clade 2.3.4.4b in 67 wild terrestrial mammals throughout the United States during April 1‒July 21, 2022. Affected mammals include 50 red foxes (Vulpes vulpes), 6 striped skunks (Mephitis mephitis), 4 raccoons (Procyon lotor), 2 bobcats (Lynx rufus), 2 Virginia opossums (Didelphis virginiana), 1 coyote (Canis latrans), 1 fisher (Pekania pennanti), and 1 gray fox (Urocyon cinereoargenteus). Infected mammals showed primarily neurologic signs. Necrotizing meningoencephalitis, interstitial pneumonia, and myocardial necrosis were the most common lesions; however, species variations in lesion distribution were observed. Genotype analysis of sequences from 48 animals indicates that these cases represent spillover infections from wild birds. |
| Databáze: | Directory of Open Access Journals |
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