Kinetics of acid-base parameters in conventional hemodialysis

Autor: J.R. Lugon, G.R.M. Pereira, J.P. Strogoff-de-Matos, A.J. Peixoto
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 52, Iss 1 (2018)
Druh dokumentu: article
ISSN: 1414-431X
1414-431x
11639024
DOI: 10.1590/1414-431x20187974
Popis: Details about the acid-base changes in hemodialysis are scarce in the literature but are potentially relevant to adequate management of patients. We addressed the acid-base kinetics during hemodialysis and throughout the interdialytic period in a cross-sectional study of adults undergoing conventional hemodialysis. Samples for blood gas analysis were obtained from the arterial limb of the arteriovenous fistula before the first session of the week (HD1), immediately at the end of HD1, and on sequential collections at 15, 30, 45, 60, and 120 min post-HD1. Additional blood samples were collected after ∼20 h following the end of the first dialysis and immediately prior to the initiation of the second dialysis of the week. Thirty adult patients were analyzed (55±15 years, 50% men, 23% diabetic; dialysis vintage 69±53 months). Mean serum bicarbonate levels increased at the end of HD1 (22.3±2.7 mEq/L vs 17.5±2.3 mEq/L, P
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