| Autor: |
Marisse Masis Solano, Remy Dumas, Mark R Lesk, Santiago Costantino |
| Jazyk: |
angličtina |
| Rok vydání: |
2025 |
| Předmět: |
|
| Zdroj: |
IEEE Open Journal of Engineering in Medicine and Biology, Vol 6, Pp 127-132 (2025) |
| Druh dokumentu: |
article |
| ISSN: |
2644-1276 |
| DOI: |
10.1109/OJEMB.2024.3453049 |
| Popis: |
Objective: To assess the impact of microgravity exposure on ocular rigidity (OR), intraocular pressure (IOP), and ocular pulse amplitude (OPA) following long-term space missions. OR was evaluated using optical coherence tomography (OCT) and deep learning-based choroid segmentation. IOP and OPA were measured with the PASCAL Dynamic Contour Tonometer (DCT). Results: The study included 26 eyes from 13 crew members who spent 157 to 186 days on the International Space Station. Post-mission results showed a 25% decrease in OPA (p < 0.005), an 11% decrease in IOP from 16.0 mmHg to 14.2 mmHg (p = 0.04), and a 33% reduction in OR (p = 0.04). No significant differences were observed between novice and experienced astronauts. Conclusions: These findings reveal previously unknown effects of microgravity on the eye's mechanical properties, contributing to a deeper understanding of Spaceflight-Associated Neuro-ocular Syndrome (SANS). Long-term space missions significantly alter ocular biomechanics and have the potential to become biomarkers of disease progression. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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