A Panel of High Resolution Melting (HRM) Technology-Based Assays with Direct Sequencing Possibility for Effective Mutation Screening of EGFR and K-ras Genes

Autor:	D. A. M. Heideman, F. B. Thunnissen, M. Doeleman, D. Kramer, H. M. Verheul, E. F. Smit, P. E. Postmus, C. J. L. M. Meijer, G.A. Meijer, P. J. F. Snijders
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Cytology QH573-671
Zdroj:	Cellular Oncology, Vol 31, Iss 5, Pp 329-333 (2009)
Druh dokumentu:	article
ISSN:	1570-5870 1875-8606
DOI:	10.3233/CLO-2009-0489
Popis:	Background: Increasing data from clinical trials support EGFR and K-ras mutation status as predictive markers of tumour response to EGFR-targeted therapies. Consequently, rapid and reliable mutation screening assays are demanded to guide rational use of EGFR-targeted therapies.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0ea96d7979ce4bb1a0a7eaa416f018b2 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF