Autor: |
Kathryn Boyd, Vinie Kouamou, Admire Hlupeni, Zorodzai Tangwena, Chiratidzo E. Ndhlovu, Azure T. Makadzange |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Microbiology Spectrum, Vol 10, Iss 4 (2022) |
Druh dokumentu: |
article |
ISSN: |
2165-0497 |
DOI: |
10.1128/spectrum.01075-22 |
Popis: |
ABSTRACT Cryptococcal disease (CD) is a leading cause of mortality among individuals with advanced HIV disease (AHD). Screening with serum cryptococcal antigen (sCrAg) lateral flow assay (LFA) enables early detection of subclinical disease but requires venipuncture and laboratory processing. Clinic-based point of care (POC) CrAg screening tests using urine or fingerprick whole blood could facilitate early diagnosis of CD. We evaluated the diagnostic performance of POC clinic-based fingerprick whole blood and urine CrAg compared to the gold standard laboratory sCrAg LFA in screening for CD among asymptomatic individuals with CD4 counts of |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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