Autor: |
Laetitia Keller, Luc Pijnenburg, Ysia Idoux-Gillet, Fabien Bornert, Laila Benameur, Maryam Tabrizian, Pierrick Auvray, Philippe Rosset, Rosa María Gonzalo-Daganzo, Enrique Gómez Barrena, Luca Gentile, Nadia Benkirane-Jessel |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-019-10165-5 |
Popis: |
Arthroplasty is the main clinical option for the treatment of osteoarticular lesions, but has limited efficacy. Here, the authors use a wound dressing with autologous mesenchymal stromal cells, functionalised for local BMP2 delivery, and show feasibility and safety in standardised preclinical tests in animal models, suggesting suitability for use in clinical trials. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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