Patient acceptability of, and attitudes towards, hepatitis B cure research – A scoping review and identification of knowledge gaps

Autor: Neaka Mohtashemi, Karine Dubé, Chloe Thio, Sihyeong Song, Shail Patel, Jeremy Sugarman, Debika Bhattacharya
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Virus Eradication, Vol 9, Iss 4, Pp 100354- (2023)
Druh dokumentu: article
ISSN: 2055-6640
DOI: 10.1016/j.jve.2023.100354
Popis: Functional cure, defined as durable loss of hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA suppression off therapy, is an increasingly important goal in the treatment of chronic hepatitis B. Although novel treatments aimed at achieving functional cure are being developed and tested in clinical trials, it is important to assess the perspectives of people living with HBV towards these potential treatments and their participation in HBV functional cure research. We have performed a scoping review that revealed that there is limited knowledge regarding patient perspectives of HBV functional cure research and then identified gaps in knowledge for further investigation. Our work highlights the need for further studies in patient perspectives in HBV functional cure research.
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