CO2 signaling mediates neurovascular coupling in the cerebral cortex

Autor: Patrick S. Hosford, Jack A. Wells, Shereen Nizari, Isabel N. Christie, Shefeeq M. Theparambil, Pablo A. Castro, Anna Hadjihambi, L. Felipe Barros, Iván Ruminot, Mark F. Lythgoe, Alexander V. Gourine
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29622-9
Popis: The mechanism of neurovascular coupling ensures that the brain energy supply is sufficient to meet demand. Here the authors show that in this mechanism CO2 plays an important role in neuronal activity-dependent regulation of local brain blood flow.
Databáze: Directory of Open Access Journals