Inherited thrombophilia secondary to protein S deficiency associated with ischemic stroke. Case report

Autor: Diana Matcau, Claudia Barsan, Traian Flavius Dan, Camelia Barbusi, Any Docu Axelerad, Dragos Catalin Jianu
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Romanian Journal of Neurology, Vol 15, Iss 4, Pp 187-191 (2016)
Druh dokumentu: article
ISSN: 1843-8148
2069-6094
DOI: 10.37897/RJN.2016.4.8
Popis: Thrombophilia is characterized by an increased tendency to arterial and venous thrombus formation. Inherited thrombophilia can be secondary to protein S deficiency. Concomitant use of oral contraceptive pills increases the risk of venous thromboembolism and arterial thrombosis. We report a case of a 34-year-old female who used oral contraceptive pills for many years, who developed acute ischemic stroke of right occipital lobe with secondary left superior homonymous quadrantanopia. We have run several tests to establish the ischemic stroke etiology: unenhanced brain and cervical spine computed tomography, brain magnetic resonance imaging and magnetic resonance angiography (including MR venography), computed tomographic angiography, echocardiography, extracranial duplex ultrasound and laboratory data (including thrombophilia testing). The laboratory investigations confirmed that the ischemic stroke of our patient resulted from a severe inherited thrombophilia secondary to protein S deficiency.
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