Evaluation of the polypill therapy effectiveness in patients with arterial hypertension and dyslipidemia who underwent COVID-19

Autor: V.E. Oleynikov, I.V. Avdeeva, K.I. Pavlenko
Jazyk: English<br />Russian
Rok vydání: 2024
Předmět:
Zdroj: Известия высших учебных заведений. Поволжский регион: Медицинские науки, Iss 4 (2024)
Druh dokumentu: article
ISSN: 2072-3032
DOI: 10.21685/2072-3032-2023-4-15
Popis: Background. To study the dynamics of blood pressure (BP), lipid profile and arterial stiffness after 12 weeks of polypill therapy, including perindopril, indapamide and rosuvastatin. Materials and methods. 40 patients with arterial hypertension (AH) and dyslipidemia who underwent COVID-19 were included. 35 persons (87.5%) completed the follow-up period. All patients had their office blood pressure measured using the Korotkov method. A biochemical blood test was performed to determine total cholesterol, highdensity lipoproteins (HDL), triglycerides (TG). The level of low-density lipoprotein cholesterol (LDL) was calculated. With the applanation tonometry, systolic (SDao), diastolic (DDao) and pulse (PDao) pressure in the aorta, carotid-femoral pulse wave velocity (PWVcf) were recorded. Results. Against the background of polypill therapy, a decrease in systolic blood pressure by 18% and diastolic blood pressure by 17% was noted for 12 weeks. The target BP (
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