Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid

Autor: T. O. Aiyelabola, D. A. Isabirye, E. O. Akinkunmi, O. A. Ogunkunle, I. A. O. Ojo
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Chemistry, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-9063
2090-9071
DOI: 10.1155/2016/7317015
Popis: Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus. The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out. This resulted in varying geometrical structures for the complexes. The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard.
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