Use of dose-area product to assess plan quality in robotic radiosurgery

Autor: Markus Eichner, Alexandra Hellerbach, Mauritius Hoevels, Klaus Luyken, Michael Judge, Daniel Rueß, Maximilian Ruge, Martin Kocher, Stefan Hunsche, Harald Treuer
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Zeitschrift für Medizinische Physik, Vol 34, Iss 3, Pp 428-435 (2024)
Druh dokumentu: article
ISSN: 0939-3889
DOI: 10.1016/j.zemedi.2023.01.001
Popis: Purpose: In robotic stereotactic radiosurgery (SRS), optimal selection of collimators from a set of fixed cones must be determined manually by trial and error. A unique and uniformly scaled metric to characterize plan quality could help identify Pareto-efficient treatment plans. Methods: The concept of dose-area product (DAP) was used to define a measure (DAPratio) of the targeting efficiency of a set of beams by relating the integral DAP of the beams to the mean dose achieved in the target volume. In a retrospective study of five clinical cases of brain metastases with representative target volumes (range: 0.5–5.68 ml) and 121 treatment plans with all possible collimator choices, the DAPratio was determined along with other plan metrics (conformity index CI, gradient index R50%, treatment time, total number of monitor units TotalMU, radiotoxicity index f12, and energy efficiency index η50%), and the respective Spearman's rank correlation coefficients were calculated. The ability of DAPratio to determine Pareto efficiency for collimator selection at DAPratio
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